Drug Poisoning: Poisoning by Antidepressants

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  • Mahshid Afshar
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Akathisia after Cyclic Antidepressants Poisoning

A 54-year-old depressive woman was admitted to the emergency department with a Glasgow Coma Scale of six (E1V1M4) and hypothermia (34°C). A drug overdose was early suspected by history as the patient was treated by tricyclic antidepressants (TCA). The maximal ingested dose was 1000 mg for amitriptyline and 8400 mg for clomipramine, and the delay from ingestion was unknown. The admission serum c...

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Cardiac abnormalities in poisoning with tricyclic antidepressants.

Of 80 consecutive admissions to a general hospital for drug overdose, 10 had taken one or other of the tricyclic antidepressants. All 10 had abnormalities of cardiac conduction as shown by prolonged Q-T(e) intervals, and eight had S-T segment and T-wave changes. Five of the 10 patients had arrhythmias and two of these died. Continuous electrocardiographic monitoring is recommended in patients w...

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Respiratory Resuscitation in Drug Poisoning

We have described the more important re­spiratory complications relating to poison­ing. Particular attention has been directed for the prevention of aspiration of stomach contents, and treatment of acid aspiration syndrome because of its poor progvosis. Re­spiratory complications may occur in 3p.c. of poisonings. In comatose patient possibility of aspiration is great. Respiratory assistance wit...

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Acute drug poisoning in children

Objective To study acute drug poisoning in Sri Lankan children. Design A prospective hospital based study. Setting Lady Ridgeway Hospital for Children, Colombo. Patients Children with suspected acute drug poisoning admitted to hospital from January 1985 to January 2000. Results There were 622 children with acute drug poisoning. 469 (75%) children were less than 4 years of age. 190 (30.5%) child...

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[Increasing significance of antidepressants in deliberate self-poisoning].

BACKGROUND AND OBJECTIVE Antidepressant drugs are frequently used in deliberate self-poisoning resulting in a major risk for the patients due to their cardiac and central-nervous toxicity. In the present study the cases of intoxications consulting our Poison Center should be analysed illustrating recent results and trends about self-poisoning with antidepressants. PATIENTS AND METHODS During ...

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Poisoning by Thevetia Nerifolia

of village Jhowa, under the jurisdiction of Contai Thana, rubbed two seeds with treacle on a mortar and swallowed them down oil the 5th of June 1897, to procure abortion. Almost immediately after taking the poison, she felt a burning pain in the throat, vomited and purged several times, became much prostrated, and had several fainting fits. She was brought to hospital by the police on the follo...

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عنوان ژورنال

دوره 5  شماره 2

صفحات  152- 156

تاریخ انتشار 1977-03

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